By George Tegos, Eleftherios Mylonakis

Drug resistance is expanding between a number of human pathogenic microorganisms equivalent to Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumaniii, Pseudomonas aeruginosa and Enterobacter spp. (currently dubbed the 'ESKAPE' pathogens), and has emerged as probably the most very important scientific demanding situations of this century. elevated basic understanding and worry of those pathogens skill there's a starting to be call for for examine to take on the specter of multidrug resistance. Documenting the newest learn within the box, this e-book discusses present and promising actions to find new antimicrobials in 5 key components: molecular genetics and platforms microbiology; artificial, computational chemistry and chemoinformatics; excessive Throughput Screening (HTS); non-vertebrate version hosts; and light-weight- and nano-based applied sciences.

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Chopra, I. W. (2010) Structure-based discovery of antibacterial drugs. Nature Reviews Microbiology 8, 501–510. , Roncucci, G. and Jori, G. (2002) Approaches to selectivity in the Zn(II)-phthalocyaninephotosensitized inactivation of wild-type and antibiotic-resistant Staphylococcus aureus. Photochemical and Photobiological Sciences 1, 815–819. Soukos, N. M. (2011) Photodynamic therapy in the control of oral biofilms. Periodontology 2000 55, 143–166. V. and Gibbons, S. (2007) Bacterial efflux pump inhibitors from natural sources.

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Antimicrobial drug discovery : emerging strategies by George Tegos, Eleftherios Mylonakis
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