By Roger S. Kirby MD FRCS(Urol) FEBU

This can be a condensed model of the author's profitable Atlas of Prostatic Disease. The emphasis is on a succinct description of prostatic illness in a mostly illustrative layout. The publication covers the motives, prognosis and staging of prostate melanoma, benign prostatic hyperplasia and prostatitis. The sections on therapy were more advantageous via the addition of algorithms to summarize the decision-making strategy.

Men's healthiness is now an incredible public future health factor and prostatic affliction could have an incredible influence at the caliber of lifetime of many males. This booklet will supply a handy precis for urologists, basic care physicians and nurse practitioners

Show description

Read or Download An illustrated pocketbook of prostatic diseases PDF

Best urology books

Smith's General Urology

Hemodynamics makes it attainable to represent in a quantitative manner, the functionality of the guts and arterial method, thereby generating information regarding what genetic and molecular methods are of value for cardiovascular functionality. Snapshots of Hemodynamics: An reduction for scientific examine and Graduate schooling by means of Nico Westerhof, Nikos Stergiopulos and Mark I.

Smith's Textbook of Endourology

Endourology is a dynamic subspecialty regarding closed, managed manipulation in the genitourinary tract. long ago decade the artistic efforts of many urologists, radiologists, and engineers have tremendously increased endoscopic procedure, to the nice advantage of sufferers with stones, obstruction, melanoma, diverticula, cysts, adrenal illness, varices, and ailments of the bladder.

Ion Channels and Transporters of Epithelia in Health and Disease

This ebook sheds new mild at the body structure, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the elemental mobile versions and capabilities via a compelling scientific point of view, addressing points from the laboratory bench to the bedside. the person chapters, written by way of best scientists and clinicians, discover particular ion channels and transporters positioned within the epithelial tissues of the kidney, gut, pancreas and respiration tract, all of which play a very important half in retaining homeostasis.

Extra info for An illustrated pocketbook of prostatic diseases

Example text

Identification of this process of invasion can be facilitated by the use of immunocyto-chemistry to delineate basal cells and the cytokeratin of the basement membrane (see Figure 3). Once invasion has occurred, the histological grading of the malignancy is accomplished by use of Gleason’s technique27, which is based on the tendency of a given tumor to form gland-like structures (Figure 35). Because of the marked heterogeneity of prostatic cancers, the Gleason score is calculated as the sum of the two most dominant histological patterns within a given cancer.

A mutation (Figure 18), resulting in a single base-pair change, causes an inability to separate GTP from the ras p21 protein, thereby locking it permanently in its activated form. The result is a continuing inappropriate signal for cell proliferation (Figure 19). Another oncogene, c-erb B-2, acts through a different mechanism. A point mutation of DNA segment coding for c-erb B-2 results in the production of a distorted version of the EGF receptor. This mutant protein has no external component, with the result that the internal component continually signals the need for cell division, regardless of the presence or absence of EGF signal molecules15.

Normally, the p53 protein is involved in the regulation of cell division. Mutation or deletion of the gene thus encourages uncontrolled cell division suppressor genes16, the best examples of which are the p53 and retinoblastoma tumor suppressor genes17,18. The p53 protein encoded by the former gene acts as an important regulator of cell division. Point mutation or complete deletion of this gene permits abnormal cell proliferation to occur (Figure 20). The p53 tumor suppressor gene has also been implicated as an important factor in the development of other cancers, including lung, breast, colon and bladder neoplasms19,20.

Download PDF sample

An illustrated pocketbook of prostatic diseases by Roger S. Kirby MD FRCS(Urol) FEBU
Rated 4.43 of 5 – based on 10 votes