By M. Brouwer, W.E.S. Carr, W. Ross Ellington, D.W. Engel, R.A. Gleeson, B. Korsgaard, T.S. Moerland, T. Mustafa, D.J. Prior, B.D. Sidell, K.C. Srivastava, H.G. Trapido-Rosenthal, R.E. Weber, R.W. Wiseman

Advances in Comparative and Environmental Physiology is helping biologists, physiologists, and biochemists maintain music of the large literature within the box. offering complete, built-in experiences and sound, serious, and provocative summaries, this sequence is a must for all lively researchers in environmental and comparative physiology.

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1987; Changeux and Rivah 1987). In the second scheme (Fig. , Berridge 1985; Levitzki 1986), an ion channel is not an integral part of the receptor molecule. In this case, the binding of the signal molecule to the receptor triggers a cascade of transduction events that begin with structural changes in a family of membrane proteins, called guanine nucleotide-binding proteins (G-proteins). Conformational changes in the G-proteins induce changes in the structure of an enzyme that enhances or inhibits the production of one of a small family of "second messenger" substances such as cyclic AMP, cyclic GMP, inositol trisphosphate, or diacylglycerol.

Chemosensory Systems of Slime Molds, Protozoa, and Yeast .................. Cellular Slime Molds: Chemosensory System for Cyclic AMP ................. Protozoa and Yeast: Chemosensory Systems for Acetylcholine, Catecholamines, and Peptides ............................................................ 3 Marine Larvae: Factors Affecting Settlement and Metamorphosis .............. 1 Natural Inducers of Larval Metamorphosis .................................

In addition to the slime mold example described earlier, external chemoreceptors sensitive to adenine nucleotides and related compounds also occur in a number of other organisms, especially insects, crustaceans, and mammals (Table 2). Of particular note are the studies in marine crustaceans demonstrating the presence of Pc and Prlike chemoreceptors that mediate detection of AMP and ATP, respectively, in seawater. The behavioral, physiological, and biochemical findings of these studies, which are summarized below, reveal striking parallels between these external purinergic systems and those described for the internal tissues of mammals.

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Advances in Comparative and Environmental Physiology by M. Brouwer, W.E.S. Carr, W. Ross Ellington, D.W. Engel, R.A.
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